Description Usage Arguments Details Value Author(s) Examples
This function is used to estimate theta assuming the gold standard biomarker is used. Further the distribution of the biomarker is assumed to be normaly distributed with a given mean and variance.
1 | thetama(mydat)
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mydat |
A data frame with the outcome variable and exposure variables |
This metric measure the decrease in the expected proportion of events that were avoided as a result of using the biomarker guided treatment. However the biomarker observed is the modified asssay rather than the gold standard assay. To reduce the computational time, a raoblackwelization method conditioning over the sufficient statistics was used.
A value in the range of 0-1.
Henok Woldu
1 2 3 | # Let the data is stored in an object named mydat
# Let dpar the parmaters of the normally distributed biomarker
modtheta <- thetama(mydat)
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