pk_solution: PK solution over dosing cycle

In hlweeks/pkpredict: Compartment Model Implementation for Pharmacokinetic Analysis

PK solution over dosing cycle

Description

The 'pk_solution' function impelments a piecewise solution to the two-compartment model, taking into account the sequence of dosing events:

Usage

pk_solution(k_10, k_12, k_21, v_1, ivt, init = c(0, 0))

Arguments

k_10	Elimination rate from central compartment
k_12	Elimination rate from central to peripheral compartment
k_21	Elimination rate from peripheral to central compartment
v_1	Volume of central compartment
ivt	List with containing start of infusion times (h), end of infusion times (h), and rate of infusion (g/h) at each dose
init	Initial concentration of drug in c(central, peripheral) compartments

Value

A function that will compute concentration of drug in the body given time since first infusion.

hlweeks/pkpredict documentation built on Oct. 29, 2023, 6:08 a.m.