echoseq-package: echoseq: a package for faithful replications and simulations...

echoseq-packageR Documentation

echoseq: a package for faithful replications and simulations of genetic variants, molecular expression levels and other phenotypic data

Description

The echoseq package provides functions to emulate molecular quantitative trait locus data and clinical data associated with genetic variants under user-specified association patterns. The data can be the result of pure simulation or can replicate real datasets supplied by the user (which may replace real data when these cannots be shared for diverse privacy reasons). The data generation schemes are based on generally accepted principles of population genetics (Hardy–Weinberg equilibrium, linkage-disequilibrium, natural selection, pleiotropic control, sparsity assumptions).

echoseq functions

convert_snps, convert_phenos, generate_dependence, generate_phenos, generate_snps, replicate_real_phenos, replicate_real_snps.


hruffieux/echoseq documentation built on Jan. 10, 2024, 10:06 p.m.