bacterial_resistance: Bacterial resistance data

In hunansona/ed4bhm: Empirical Determinacy for Bayesian Hierarchical Models

Bacterial resistance data

Description

Strains of E. coli, which were isolated from 2010 until 2014 in the laboratory of the Institute for Medical Microbiology at the University of Zurich, are considered. Inhibition zone diameter (IZD) values in (mm) for the antibiotics Amoxicillin-clavulanic acid (AMC), Ceftriaxone (CRO), and Imipenem (IPM). IZD can attain values between 6 (mm) and 40 (mm).

Usage

data(bacterial_resistance)

Format

A data frame with 35 observations on the following 8 variables.

IZD

numeric, inhibition zone diameter (IZD) values in (mm). IZD can attain values between 6 (mm) and 40 (mm).

scIZD

numeric, inhibition zone diameter (IZD) values scaled to have mean 0 and standard deviation 1.

ncrowt

numeric, counts for the wilde-type isolates for the antibiotic CRO.

ncroesbl

numeric, counts for the ESBL isolates for the antibiotic CRO.

nipmwt

numeric, counts for the wilde-type isolates for the antibiotic IPM.

nipmesbl

numeric, counts for the ESBL isolates for the antibiotic IPM.

namcwt

numeric, counts for the wilde-type isolates for the antibiotic AMC.

namcesbl

numeric, counts for the ESBL isolates for the antibiotic AMC.

Details

These isolates were identified as resistant (ESBL) and susceptible (wild-type) bacteria through antimicrobial susceptibility testing (AST). For AST, bacterial isolates are brushed on agar plates. An antibiotic is provided on a disk in the middle of the agar plate. After eight hours of incubation, the inhibition zone diameter (IZD) is quantified.

Source

G. Valsesia, M. Hombach, F.P. Maurer, P. Courvalin, M. Roos, and E.C. Boettger. The resistant-population cutoff (RCOFF): a new concept for improved characterization of antimicrobial susceptibility patterns of non-wild-type bacterial populations. Journal of Clinical Microbiology, 53(6):1806-1811, 2015a.

References

G. Valsesia, M. Roos, E.C. Boettger, and M. Hombach. A statistical approach for determination of disk diffusion-based cutoff values for systematic characterization of wild-type and non-wild-type bacterial populations in antimicrobial susceptibility testing. Journal of Clinical Microbiology, 53(6):1812-1822, 2015b.

Examples

data(bacterial_resistance)
str(bacterial_resistance)

hunansona/ed4bhm documentation built on June 15, 2022, 6:42 p.m.