macc: A function to compute MNase accessibility (MACC) scores.

Description Usage Arguments Examples

Description

A function to compute MNase accessibility (MACC) scores.

Usage

1
2
macc(tags.in.bins = NULL, tit.points = NULL, gc.cont = NULL,
  chrn = NULL, chr.stat = NULL, mc.cores = 2, bin = 300, CpG = NULL)

Arguments

tags.in.bins

an list returned by count.tags.in.bins function and contatining localization of bins and number of tags in each of the selected bins.

tit.points

a vector of MNase concentrations used in the experiment. The concentrations should be provided in ascending order.

gc.cont

a list of vectors containing information about GC content. Each vector corresponds to different chromosome.

chrn

a vector of chromosome names or NULL for all chromosomes.

chr.stat

a data.frame with sizes of analyzed chromosmes.

mc.cores

a number of cores for parallel computing.

bin

a size of a bin.

CpG

a GenomeRanges object with localization of CpG island.

scale.genome.to.100Mb

logical. Should the values be normalized to genome size?

normalize.perBinSize

logical. Should the values be normalized to been size?#' @keywords MACC

Examples

1
macc()

jakubmie/MACC documentation built on May 18, 2019, 11:17 a.m.