jamesware/denovolyzeR: Statistical Analyses of De Novo Genetic Variants
Version 0.2.0

An integrated toolset for the analysis of de novo (sporadic) genetic sequence variants. denovolyzeR implements a mutational model that estimates the probability of a de novo genetic variant arising in each human gene, from which one can infer the expected number of de novo variants in a given population size. Observed variant frequencies can then be compared against expectation in a Poisson framework. denovolyzeR provides a suite of functions to implement these analyses for the interpretation of de novo variation in human disease.

Getting started

Package details

Maintainer
LicenseGPL-3
Version0.2.0
URL http://denovolyzeR.org
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("devtools")
library(devtools)
install_github("jamesware/denovolyzeR")
jamesware/denovolyzeR documentation built on May 17, 2017, 9:43 a.m.