td2pLL: Calculate response value for given td2pLL model

In jcduda/td2pLL: Fitting a time-dose two-parameter log-logistic model to time-dose-response data

Calculate response value for given td2pLL model

Description

td2pLL returns the response value of a fully specified time-dose two-parameter log-logistic model at a certain time (t) and dose (d) value:

f(d,t)=100-100\frac{d^h}{EC_{50}(t)^h + d^h}

with

EC_{50}(t) = Δ \cdot t^{-γ} + C_0

Usage

td2pLL(time, dose, h, gamma, c0, delta)

Arguments

time	(numeric(1)) Time value at which the response shall be calculated. Must be greater than 0.
dose	numeric for the dose (or concentration) value where the response shall be calculated
h	(numeric(1)) The h parameter of the model.
gamma	(numeric(1)) The gamma parameter of the model.
c0	(numeric(1)) The c0 parameter of the model.
delta	(numeric(1)) The delta parameter of the model.

Value

(numeric(1))
The response value of the model in percent at the given time and dose value.

Examples

 td2pLL(time = 4, dose = 0.1, h = 2, gamma = 2.5, c0 = 0.1, delta = 0.3)

jcduda/td2pLL documentation built on May 14, 2022, 6:48 p.m.