Description Objects from the Class Slots Methods Author(s) References See Also Examples
A class to represent Probe Level Models.
Objects can be created by calls of the form
fitProbeLevelModel(FeatureSetObject)
, where
FeatureSetObject
is an object obtained through
read.celfiles
or read.xysfiles
, representing intensities
observed for different probes (which are grouped in probesets or
meta-probesets) across distinct samples.
chip.coefs
:"matrix"
with chip/sample effects -
probeset-level
description
:"MIAME"
compliant description
information.
phenoData
:"AnnotatedDataFrame"
with phenotypic
data.
protocolData
:"AnnotatedDataFrame"
with
protocol data.
probe.coefs
:"numeric"
vector with probe effects
weights
:"matrix"
with weights - probe-level
residuals
:"matrix"
with residuals - probe-level
se.chip.coefs
:"matrix"
with standard errors
for chip/sample coefficients
se.probe.coefs
:"numeric"
vector with standard
errors for probe effects
residualSE
:scale - residual standard error
geometry
:array geometry used for plots
method
:"character"
string describing method
used for PLM
manufacturer
:"character"
string with manufacturer name
annotation
:"character"
string with the name of
the annotation package
narrays
:"integer"
describing the number of arrays
nprobes
:"integer"
describing the number of
probes before summarization
nprobesets
:"integer"
describing the number of
probesets after summarization
signature(object = "oligoPLM")
:
accessor/replacement method to annotation slot
signature(x = "oligoPLM")
: boxplot method
signature(object = "oligoPLM")
:
accessor/replacement method to coef slot
signature(object = "oligoPLM")
:
accessor/replacement method to coefs.probe slot
signature(object = "oligoPLM")
:
accessor/replacement method to geometry slot
signature(x = "oligoPLM")
: image method
signature(object = "oligoPLM")
:
accessor/replacement method to manufacturer slot
signature(object = "oligoPLM")
:
accessor/replacement method to method slot
signature(x = "oligoPLM")
: accessor/replacement
method to ncol slot
signature(object = "oligoPLM")
:
accessor/replacement method to nprobes slot
signature(object = "oligoPLM")
:
accessor/replacement method to nprobesets slot
signature(object = "oligoPLM")
:
accessor/replacement method to residuals slot
signature(object = "oligoPLM")
:
accessor/replacement method to residualSE slot
signature(object = "oligoPLM")
:
accessor/replacement method to se slot
signature(object = "oligoPLM")
:
accessor/replacement method to se.probe slot
signature(object = "oligoPLM")
: show method
signature(object = "oligoPLM")
:
accessor/replacement method to weights slot
signature(x = "oligoPLM")
: Boxplot of Normalized
Unscaled Standard Errors (NUSE) or NUSE values.
signature(x = "oligoPLM")
: Relative Log Expression
boxplot or values.
signature(x = "oligoPLM")
: Convert to ExpressionSet.
This is a port from Ben Bolstad's work implemented in the affyPLM package. Problems with the implementation in oligo should be reported to the package's maintainer.
Bolstad, BM (2004) Low Level Analysis of High-density Oligonucleotide Array Data: Background, Normalization and Summarization. PhD Dissertation. University of California, Berkeley.
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