Description Usage Arguments Details

Function to obtain quasi-correlation estimates given

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`testBetas` |
Univariate effect sizes for the out-of-sample data |

`testSes` |
Univariate standard errors for the effect sizes of the out-of-sample data |

`N` |
Sample sizes corresponding to the testBetas. Can be a constant or a vector. |

`penalizedBetas` |
The polygenic risk scores to be tested on the out-of-sample data. May be a matrix. |

`refPanel` |
PLINK stem for binary file to be used as the reference panel |

`allele1` |
Vector of effect alleles for the penalizedBetas. Corresponds to the fifth column of a PLINK .bim file. |

`allele2` |
Vector of reference alleles for the penalizedBetas. Corresponds to the sixth column of a PLINK .bim file. |

`standardized` |
Set to true if the coefficient estimates for penalizedBetas are standardized. Note that elastSum and tlpSum output standardized estimates. |

`trainVar` |
Phenotypic variance for data used to estimate the penalizedBetas. Only necessary if standardized = TRUE |

`allele1.test` |
Vector of effect alleles for the testBetas. Corresponds to the fifth column of a PLINK .bim file. |

`allele2.test` |
Vector of reference alleles for the testBetas. Corresponds to the sixth column of a PLINK .bim file. |

`ldBlocks` |
Location of file specifying independent LD Blocks to be used. File should be in the BED file format. If null, estimation is done by chromosome. |

Function requires univariate effect size estimates, standard errors, and sample sizes, candidate polygenic risk score estimates, and a reference panel.

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