OU_approx: Ornstein Uhlenbeck Approximation to Family-Wise Error Rate

In kegrinde/STEAM: Significance Threshold Estimation for Admixture Mapping

Ornstein Uhlenbeck Approximation to Family-Wise Error Rate

Description

Analytic approximation to the family-wise error rate for test statistics arising from Ornstein-Uhlenbeck process. Approximation courtesy of: Siegmund and Yakir (2007). The statistics of gene mapping.

Usage

OU_approx(z, beta, Delta, length, chr, center, test)

Arguments

z	the critical value.
beta	the OU covariance parameter.
Delta	the spacing between markers.
length	the total length of the region.
chr	the number of chromosomes.
center	the level for family-wise error rate.
test	the type of test ("two-sided" or "one-sided").

Value

A single number indicating the distance between the family-wise error rate using critical value z and the desired level (center).

Examples

OU_approx(4.277817, 0.01*6, 0.2, 3500, 22, 0.05, "two-sided")

kegrinde/STEAM documentation built on June 30, 2024, 11:27 p.m.