get.observed.data.GxE: Generates exposure data with some error

In kwesterman/ESPRESSO.GxE.RV: Power analysis and sample size calculation for a multi-variant gene-environment interaction model

Generates exposure data with some error

Description

Uses functions make.obs.geno and make.obs.env to generate effect data with a set level of error

Usage

get.observed.data.GxE(
  data = NULL,
  g.error = NULL,
  g.model = NULL,
  freq = NULL,
  e.error = NULL,
  e.model = NULL,
  e.prev = NULL,
  e.sd = NULL,
  e.reliability = NULL
)

Arguments

data	Input table of simulated data considered as true data
g.error	Misclassification rates in genetic assessment: 1-sensitivity and 1-specificity
g.model	Genetic model; 0 for binary and 1 for additive
freq	Minor allele frequency
e.error	Misclassification rates in environmental exposures assessment: 1-sensitivity and 1-specificity
e.model	Model of the exposure: binary=0, quantitative-normal=1 or quantitative-uniform=2
e.prev	Prevalence of environmental exposure
e.sd	Standard Deviation
e.reliability	Reliability of the assessment of quantitative exposure

Value

A matrix

Author(s)

Gaye A.; Westerman K.

kwesterman/ESPRESSO.GxE.RV documentation built on Aug. 27, 2023, 4:44 a.m.