sim.geno.data: Generates genotypes for a genetic variant

In kwesterman/ESPRESSO.GxE.RV: Power analysis and sample size calculation for a multi-variant gene-environment interaction model

Generates genotypes for a genetic variant

Description

Generates two alleles and combines them to form the genotype of a SNP under a binary or additive genetic model.

Usage

sim.geno.data(num.obs = NULL, geno.model = NULL, MAF = NULL)

Arguments

num.obs	number of observations to generate.
geno.model	genetic model; binary=0 and additive=1.
MAF	minor allele frequency of the SNP (in ESPRESSO this is the frequency of the 'at risk' allele)

Value

a dataframe that contains the following variables: allele.A major allele allele.B minor allele genotype genotype

Author(s)

Gaye A.

kwesterman/ESPRESSO.GxE.RV documentation built on Aug. 27, 2023, 4:44 a.m.