UNEQUALCENSIMPUTECOXREJECTION: UNEQUALCENSIMPUTECOXREJECTION

In lbeesleyBIOSTAT/MultiCure: EM Algorithms for Fitting Multistate Cure Models

Description

The function UNEQUALCENSIMPUTECOXREJECTION will perform an imputation algorithm to handle unequal follow-up for recurrence and death. This function can be applied when we assume COX baseline hazards. This function performs imputation through rejection sampling.

Usage

UNEQUALCENSIMPUTECOXREJECTION(datWIDE, beta, alpha, ImputeDat, TransCov)

Arguments

datWIDE	defined as in MultiCure
beta	A vector containing the most recent estimates of beta
alpha	A vector containing the most recent estimates of alpha
ImputeDat	This is a list with the following elements: UnequalCens: A vector taking value 1 if the subject has unequal follow-up. Note: If subject is assumed cured in datWIDE, they are listed as UnequalCens = 0. CovMissing: A matrix indicating which elements of Cov are missing. Not needed for this imputation. CovImp: A list containing a single imputation of Cov GImp: A vector with a recent single imputation of G YRImp: A vector with a recent single imputation of Y_R deltaRImp: A vector with a recent single imputation of delta_R y: The integral of the target kernel over Yr0 to Yd Basehaz13: A matrix containing the estimate of the baseline hazard function for the 1->3 transition specified intervals Basehaz24: A matrix containing the estimate of the baseline hazard function for the 2->4 transition specified intervals Basehaz14: A matrix containing the estimate of the baseline hazard function for the 1->4 transition specified intervals Basehaz34: A matrix containing the estimate of the baseline hazard function for the 3->4 transition specified intervals
TransCov	defined as in MultiCure

Details

This function cannot be applied when 'T_R' is included in the model for Recurrence -> Death. In this case, use one of the following functions instead UNEQUALCENSIMPUTECOXNESTEDWEIBULL, UNEQUALCENSIMPUTECOXMH or UNEQUALCENSIMPUTECOXINVERSION.

Value

a list containing

• [[1]]: deltaRImp, A single imputation of delta_R

• [[2]]: YRImp, A single imputation of Y_R

lbeesleyBIOSTAT/MultiCure documentation built on July 10, 2019, 5:27 a.m.