Description Usage Arguments Value

Optimize N and R

1 2 3 4 | ```
designOptim(EDR.result, pilot.R, R = c(1/10, 1/8, 1/6, 1/4, 1/2, 1, 1.5,
2), N = seq(4, 50, 2), targetEDR = NULL, budget = NULL,
price_per_lane = 1500, fix_price_per_sample = 300,
depth_per_lane = 250)
``` |

`EDR.result` |
a MethylSeqDesign object |

`pilot.R` |
the sequencing depth of pilot data in number of lanes |

`R` |
the targeted sequencing depth in number of lanes, input can be a vector. |

`N` |
the targeted sample size per group, input can be a vector. |

`targetEDR` |
the target EDR to achieve |

`budget` |
the budget limit |

`price_per_lane` |
the price per lane for Methyl-Seq |

`fix_price_per_sample` |
the fixed part of the price per sample including the bisulfite treatment |

`depth_per_lane` |
the total number of reads per lane in millions |

a list of three elements. The first element gives the best N and R combination, and optimal EDR/cost given budget/target EDR. The second element is a plot of admissible/inadmissible N and R combinations. The third element is a plot of cost and EDR.

Embedding an R snippet on your website

Add the following code to your website.

For more information on customizing the embed code, read Embedding Snippets.