HIV_Simu_Dataset_Delta025_cens: HIV RNA Load Simulated Data for Delta AUC = -0.25 With...

In marie-alexandre/AUCcomparison: Statistical test - Between group comparison of AUC

Description

This dataset gives simulated longitudinal log-transformed HIV RNA load dynamics for two distinct groups of patients who interrupted their antiretroviral treatment at baseline (time=0). The group 'Group1' was simulated to mimic a control group while the group 'Group2' gathers patients assigned to a treatment group. Each group accounts for 20 patients and each of them were followed for 24 weeks with one measure every week. HIV RNA load values are left-censored due to a limit of detection (LOD), considering log10(50) as threshold value. This dataset was simulated to obtain a difference of area under the mean HIV RNA load curves between the two groups (AUC2 - AUC1) equals to -0.25 log10 cp/ml.

Usage

HIV_Simu_Dataset_Delta025_cens

Format

A data frame with 4 columns and 1000 rows:

id	The subject id.
time	Time of HIV RNA load measurements.
Group	Treatment group.
VL	The HIV RNA load measures. Measures are either equals to their true value (if VL > LOD) or to the LOD value (otherwise).
Cens	The indicator of left-censoring: 1 if VLtrue <= LOD and 0 otherwise.

Details

A dataset containing simulated data used in the accompanying paper to this package.

Examples

HIV_Simu_Dataset_Delta025_cens

marie-alexandre/AUCcomparison documentation built on Dec. 21, 2021, 1:52 p.m.