bd_extract: Extract data from blooddata objects

In mathesong/kinfitr: Kinetic Modelling of PET Time Activity Curves

Extract data from blooddata objects

Description

Pull out data for modelling purposes.

Usage

bd_extract(
  blooddata,
  output = c("Blood", "BPR", "parentFraction", "AIF"),
  startTime = 0,
  stopTime = NULL,
  interpPoints = 6000,
  what = c("raw", "pred", "interp"),
  bpr_peakfrac_cutoff = 0.001
)

Arguments

blooddata	The blooddata object.
output	What curve should be extracted. It can be "Blood", "BPR" (whole-blood-to-plasma-ratio), "parentFraction" or "AIF".
startTime	The starting time for the interpolation. Defaults to zero. If, after application of the TimeShift value in the blooddata object, the startTime is still after zero, it will be set to zero.
stopTime	The end time for the interpolation. Defaults to the maximum measured time.
interpPoints	The number of points to interpolate over between the start and stop times. Defaults to 6000.
what	What kind of data should be extracted? The "raw" data is the unaltered data for modelling, the "pred" data is the predicted data at the times of the original samples for assessing correspondence, and the "interp" values are the values interpolated through the interptimes.
bpr_peakfrac_cutoff	What is the lowest permissible value of the blood or plasma curves as a fraction of the peak that should be included in the raw BPR extraction for modelling. This is to avoid ratios which tend towards 0 or Inf at early time points when blood and plasma are very low.

Value

A tibble with the relevant data

Author(s)

Granville J Matheson, [e-mail]

Examples

## Not run: 
bd_extract(blooddata, output="parentFraction", what="raw")

## End(Not run)

mathesong/kinfitr documentation built on Nov. 27, 2024, 1:38 a.m.