frtm_model: Model: Full Reference Tissue Model

In mathesong/kinfitr: Kinetic Modelling of PET Time Activity Curves

Model: Full Reference Tissue Model

Description

This is the FRTM model itself by which predicted values are generated.

Usage

frtm_model(t_tac, reftac, R1, k2, bp, k4)

Arguments

t_tac	Numeric vector of times for each frame in minutes. We use the time halfway through the frame as well as a zero.
reftac	Numeric vector of radioactivity concentrations in the reference tissue for each frame.
R1	Parameter value for R1
k2	Parameter value for k2
bp	Parameter value for bp
k4	Parameter value for k4

Value

A numeric vector of the predicted values of the TAC in the target region.

Author(s)

Granville J Matheson, [e-mail]

References

Cunningham, Vincent J., et al. "Compartmental analysis of diprenorphine binding to opiate receptors in the rat in vivo and its comparison with equilibrium data in vitro." Journal of Cerebral Blood Flow & Metabolism 11.1 (1991): 1-9.

Examples

## Not run: 
frtm_model(t_tac, reftac, R1 = 0.9, k2 = 0.1, bp = 1.5, k4 = 0.1)

## End(Not run)

mathesong/kinfitr documentation built on Jan. 15, 2024, 11:07 p.m.