Description Usage Arguments Value
Linear combination function
1 | linearcomb(type, dose_1, dose_2, e0, theta1, theta2, theta12)
|
type |
data type, "binomial" or "continuous" |
dose_1 |
combination dose 1 |
dose_2 |
combination dose 2 |
e0 |
placebo effect, logit scale for binomial data |
theta1 |
monotherapy slope for dose1, logit scale for binomial data |
theta2 |
monotherapy slope for dose 2, logit scale for binomial data |
theta12 |
interaction term, < 0 for antagonism, 0 for additivity, >0 for synergism |
single combination probability
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