mvaniterson/bacon: Controlling bias and inflation in association studies using the empirical null distribution

Bacon can be used to remove inflation and bias often observed in epigenome- and transcriptome-wide association studies. To this end bacon constructs an empirical null distribution using a Gibbs Sampling algorithm by fitting a three-component normal mixture on z-scores.

Getting started

Package details

AuthorMaarten van Iterson [aut, cre], Erik van Zwet [ctb]
Bioconductor views BatchEffect Bayesian GenomeWideAssociation ImmunoOncology MethylationArray MultipleComparison RNASeq Regression StatisticalMethod Transcriptomics
MaintainerMaarten van Iterson <mviterson@gmail.com>
LicenseGPL (>= 2)
Version1.31.1
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("mvaniterson/bacon")
mvaniterson/bacon documentation built on April 19, 2024, 5:32 p.m.