Bacon can be used to remove inflation and bias often observed in epigenome- and transcriptome-wide association studies. To this end bacon constructs an empirical null distribution using a Gibbs Sampling algorithm by fitting a three-component normal mixture on z-scores.
Package details |
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Author | Maarten van Iterson [aut, cre], Erik van Zwet [ctb] |
Bioconductor views | BatchEffect Bayesian GenomeWideAssociation ImmunoOncology MethylationArray MultipleComparison RNASeq Regression StatisticalMethod Transcriptomics |
Maintainer | Maarten van Iterson <mviterson@gmail.com> |
License | GPL (>= 2) |
Version | 1.31.1 |
Package repository | View on GitHub |
Installation |
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