A SummarizedExperiment containing PSI values of 5,000 AS events. We downloaded RNA-Seq reads of 82 MDS patients from GEO database (GSE114922), aligned with STAR, and computed PSI values using rMATS. AS events with a lot of missing values or extreme values, or those on genes with low expression were filtered out and 5,000 most variable AS events were selected.
An object of class
SummarizedExperiment with 10000 rows and 40 columns.
Pellagatti, A. et al. (2018). Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations. Blood, 132.
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