Prediction of differential gene essentiality from pooled phenotypic screens (eg: siRNA, shRNA, CRISPR/Cas9 screens) using linear mixed effect models.

Global functions | |
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addPrecisionWeights | Source code |

addSignalProbWeights | Source code |

applyFDR | Source code |

assignWeightsToObservations | Source code |

combineResults | Source code |

extractData | Source code |

fitAnova | Source code |

fitIsogenicCovariateGene | Source code |

fitIsogenicCovariateRg | Source code |

fitModel | Source code |

fitModelAndFormatOutput | Source code |

fitPanelCovariateGene | Source code |

fitPanelCovariateRg | Source code |

fitSimplerRandomEffects | Source code |

formatOutput | Source code |

getDefaultVariableMap | Source code |

getMeanSd | Source code |

getMeanVar | Source code |

getMinimalSummary | Source code |

getModelFormulas | Source code |

getModelPValues | Source code |

getRelativeDropout | Source code |

getRelativeDropoutRates | Source code |

getReplicateMeanVar | Source code |

getSignalProb | Source code |

getVarianceWeights | Source code |

loadMeanVar | Source code |

pvaluesNorm | Source code |

pvaluesT | Source code |

resetFactorLevels | Source code |

simem | Source code |

simemAnalysis | Source code |

simemChunk | Source code |

simemIsogenic | Source code |

standardizeColumnNames | Source code |

summaryAnova | Source code |

summaryFitEffectCoefs | Source code |

summaryFitLogLik | Source code |

tryCatchWarningsErrors | Source code |

volcanoPlot | Source code |

withinBetweenDF | Source code |

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