MoPPro: Estimation of metabolic profile(s) based on Taxy-Pro...

Description Usage Arguments Details Value Author(s) References

View source: R/MoPPro.R

Description

Estimation of metabolic profile(s) based on Taxy-Pro predictions from whole metagenome shotgun data

Usage

1
MoPPro(MoPProInput, folderReferenceData)

Arguments

MoPProInput

(required): list containing the taxonomic profile and sample name(s), e.g. imported with the function importTaxyProData.

folderReferenceData

(required): a character vector with one character string indicating the folder location of the unzipped reference data.

Details

MoP-Pro, a mixture model-based approach for the estimation of pathway abundances, provides a basis for statistical interpretation and fast computation of metabolic profiles of metagenomes. To overcome computationally intense homology searches, MoP-Pro implements a shortcut to estimate the metabolic profile of a metagenome. The taxonomic profile of the metagenome is linked to a set of pre-computed metabolic reference profiles. The combination of the taxonomic abundance estimates, obtained through the fast method Taxy-Pro, and the metabolic reference profiles, based on the KEGG database, achieves an unrivaled speed of the metabolic profiling approach.

Value

A vector/matrix containing the estimated metabolic profile(s)

Author(s)

Kathrin P. Asshauer kathrin@gobics.de

References

http://drops.dagstuhl.de/opus/volltexte/2013/4238/pdf/p001-asshauer.pdf


nick-youngblut/Tax4Fun documentation built on July 14, 2019, 9:32 p.m.