Man pages for nkurzaw/TPP2D
FDR-controlled analysis of 2D-TPP experiments

annotateDataListAnnotate imported data list using a config table
bootstrapNullBootstrap null distribution of F statistics for FDR...
competeModelsCompete H0 and H1 models per protein and obtain F statistic
computeFdrCompute FDR for given F statistics based on true and null...
computeFstatCompute F statistic from H1 and H0 model characteristics
config_tabExample config table for a import of a simulated 2D-TPP cell...
configWide2LongTranform configuration table from wide to long
filterOutContaminantsFilter out contaminants
findHitsFind hits according to FDR threshold
fitAndEvalDatasetFit H0 and H1 model to 2D thermal profiles of proteins and...
fitH0ModelFit H0 model and evaluate fit statistics
fitH1ModelFit H1 model and evaluate fit statistics
gg_qqPlot qq-plot of true data and bootstrapped null with ggplot
import2dDatasetImport 2D-TPP dataset using a config table
import2dMainImport 2D-TPP dataset main function
moderateOutliersModerate outlier measurements
plot2dTppFitPlot H0 or H1 fit of 2D thermal profile intensities of a...
plot2dTppProfilePlot 2D thermal profile intensities of a protein of choice
plot2dTppRelProfilePlot 2D thermal profile ratios of a protein of choice
raw_dat_listExample raw data for a subset of a simulated 2D-TPP cell...
recomputeSignalFromRatiosRecompute robust signal intensities based on bootstrapped TMT...
renameColumnsRename columns of imported data frame
simulated_cell_extract_dfExample subset of a simulated 2D-TPP cell extract dataset
TPP_importCheckConfigTableImport and chech configuration table
nkurzaw/TPP2D documentation built on June 27, 2019, 3:30 a.m.