findHits: Find hits according to FDR threshold

In nkurzaw/TPP2D: Detection of ligand-protein interactions from 2D thermal profiles (DLPTP)

Find hits according to FDR threshold

Description

Find hits according to FDR threshold

Usage

findHits(fdr_df, alpha)

Arguments

fdr_df	data frame obtained from computeFdr
alpha	significance threshold, default is set to 0.1

Value

data frame of significant hits at FDR <= alpha

Examples

data("simulated_cell_extract_df")
temp_df <- simulated_cell_extract_df %>% 
  filter(clustername %in% paste0("protein", 1:5)) %>% 
  group_by(representative) %>% 
  mutate(nObs = n()) %>% 
  ungroup 
example_out <- fitAndEvalDataset(temp_df)
example_null <- bootstrapNull(temp_df, B = 1)
fdr_df <- getFDR(example_out, example_null)
findHits(fdr_df, 0.1)

nkurzaw/TPP2D documentation built on May 9, 2023, 10:04 a.m.