tests/testthat/test-newind.R

In nlmixr2/rxode2: Facilities for Simulating from ODE-Based Models

rxTest({
  if (!.Call(`_rxode2_isIntel`)) {
    # test newind flag
    ode.1c <- rxode2({
      V <- 20
      Cl <- 1
      fc <- 1
      C2 <- center / V
      ni <- newind
      ni2 <- NEWIND
      d / dt(center) ~ -Cl * C2
      f(center) <- fc
    })

    et <- eventTable() %>%
      add.dosing(dose = 3, nbr.doses = 6, dosing.interval = 8) %>%
      add.sampling(0:4)

    et2 <- eventTable() %>%
      add.dosing(start.time = 0.5, dose = 3, nbr.doses = 6, dosing.interval = 8) %>%
      add.sampling(0:4)

    ms <- c("liblsoda", "lsoda", "dop853")

    for (m in ms) {
      s <- solve(ode.1c, et, addDosing = TRUE, method = m)
      test_that("ode newind works with dose first", {
        expect_equal(s$ni[1], 1L)
        expect_equal(s$ni2[1], 1L)
        expect_true(all(s$ni[-1] == 2))
        expect_true(all(s$ni2[-1] == 2))
      })

      s2 <- solve(ode.1c, et2, addDosing = TRUE, method = m)

      test_that("ode newind works with dose first", {
        expect_equal(s2$ni[1], 1L)
        expect_equal(s2$ni2[1], 1L)
        expect_true(all(s2$ni[-1] == 2))
        expect_true(all(s2$ni2[-1] == 2))
      })
    }
  }
})