rxTest({
ms <- c("liblsoda", "lsoda", "dop853")
for (m in ms) {
# context(sprintf("Test turning compartment off (%s)", m))
mod1 <- rxode2({
KA <- 2.94E-01
CL <- 1.86E+01
V2 <- 4.02E+01
Q <- 1.05E+01
V3 <- 2.97E+02
Kin <- 1
Kout <- 1
EC50 <- 200
C2 <- centr / V2
C3 <- peri / V3
d / dt(depot) <- -KA * depot
d / dt(centr) <- KA * depot - CL * C2 - Q * C2 + Q * C3
d / dt(peri) <- Q * C2 - Q * C3
d / dt(eff) <- Kin - Kout * (1 - C2 / (EC50 + C2)) * eff
})
et <- eventTable() %>%
add.dosing(dose = 10000, nbr.doses = 2, dosing.interval = 8) %>%
et(cmt = "-depot", time = 4) %>%
add.sampling(seq(0, 24, by = 0.5))
x <- rxSolve(mod1, et, method = m)
test_that("off works correctly", {
expect_equal((x %>% dplyr::filter(time == 4.5))$depot, 0)
expect_false((x %>% dplyr::filter(time == 4.5))$centr == 0)
})
}
})
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.