R/brca1.r

#' Breast cancer gene expression data from The Cancer Genome Atlas
#' 
#' @description
#' 
#' This data set comes from breast cancer tissue samples deposited to The Cancer
#' Genome Atlas (TCGA) project.  TCGA contains data on tumour samples were assayed
#' on several platforms; this data set compiles results obtained using Agilent mRNA
#' expression microarrays.
#' 
#' BRCA1 is the first gene identified that increases the risk of early onset breast
#' cancer.  Because BRCA1 is likely to interact with many other genes, including
#' tumor suppressors and regulators of the cell division cycle, it is of interest
#' to find genes with expression levels related to that of BRCA1, which we treat as
#' the outcome of this analysis. These genes may be functionally related to BRCA1
#' and are useful candidates for further studies.
#' 
#' Expression measurements of 17,814 genes from 536 patients; all expression
#' measurements are recorded on the log scale.  There are are 491 genes with
#' missing data, which we have excluded.
#' 
#' @format
#' 
#' * `y`: Gene expression measurement for BRCA1
#' 
#' * `X`: A matrix with 536 rows and 17322 columns of gene expression
#'   measurements for remaining genes
#' 
#' * `fData`: Additional information (chromosome and gene name) about the features
#' 
#' ### Annotation
#' 
#' * Columns of X are labeled with the Gene Symbol.
#' 
#' @source
#' 
#' [The Cancer Genome Atlas](http://cancergenome.nih.gov).
#' 
#' @name brca1
NULL
pbreheny/hdrm documentation built on July 4, 2025, 12:04 p.m.