dmrff.pre: dmrff.pre

In perishky/dmrff: Identifying differentially methylated regions efficiently with power and control

dmrff.pre

Description

Construct an object for including this dataset in a DMR meta-analysis.

Usage

dmrff.pre(estimate, se, methylation, chr, pos, maxsize = 20, verbose = T)

Arguments

estimate	Vector of association effect estimates (corresponds to rows of methylation).
se	Vector of standard errors of the effect estimates.
methylation	Methylation matrix (rows=features, columns=samples).
chr	Feature chromosome (corresponds to rows of methylation).
pos	Feature chromosome position.
maxsize	Maximum number of CpG sites in a DMR.
verbose	If TRUE (default), then output status messages.

Details

Warning! Ensure that the order of the CpG sites corresponding to the the rows of 'methylation' match the order of the CpG sites corresponding to the other variables, e.g. 'estimate' and 'chr'.

Value

A list object containing all information needed for inclusion in a meta-analysis.

perishky/dmrff documentation built on July 19, 2024, 5:16 a.m.