tcp.lqp.train: TCP (Biological Dose, Poissonian Model, Variable fractions)

In planit-group/Rplanit: Radiotherapy with ion beams - planning, simulations and analysis

TCP (Biological Dose, Poissonian Model, Variable fractions)

Description

TCP evaluation from the biological dose, using arbitrary set of fractions.

Usage

tcp.lqp.train(dvhs, D50 = 66, R = 10, gam = 2, d = 2,
  alphaX = NULL, betaX = NULL, RBE = 1)

Arguments

dvhs	a list of biological dose DVHs
D50, R, gam	tissue specific biological parameters: tolerance dose at 50%, R=alphaX/betaX, clonogenic density
d	dose per fraction
RBE	Relative Biological Effectivenes
Nf	number of fractions

Details

The total treatment correspond to a "train" of acute doses distribution (with no time correlation, i.e. full-repair is assumed). The biological dose distribution, for each voxel, can be different among fractions. Hence a list of DVH objects is needed. Each element of the list correspond to a DHV evaluated for a specific fraction.

By default it is assumed that the dvh.dose contains the biological dose dvh [Gy(E)]. Alternatively it could contain the "physical" dose [Gy] and the biological dose is evaluated by specifying the RBE per fraction (assumed to be constant over the irradiated volume).

If alphaX and betaX are not explicity defined, they were deduced from D50, gam and R.

Value

The TCP value

See Also

Other General TCP/NTCP Models: ntcp.S, ntcp.kallman.train, ntcp.kallman, tcp.S, tcp.lqp

planit-group/Rplanit documentation built on Dec. 5, 2022, 11:10 p.m.