This function calculates the ratio of True Positives to the sum of False Positives and False Negatives given a matrix of p-values (one for each statistical test used) and a vector of ground truth (DE or non-DE). This function serves as a method evaluation helper.
calc.otr(truth, p, sig = 0.05)
the ground truth differential
expression vector. It should contain only
zero and non-zero elements, with zero denoting
non-differentially expressed genes and non-zero,
differentially expressed genes. Such a vector
can be obtained for example by using the
a p-value matrix whose rows correspond
to each element in the
a significance level (0 <
A named list with two members. The first member is a data frame with the numbers used to calculate the TP/(FP+FN) ratio and the second member is the ratio TP/(FP+FN) for each statistical test.
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