Description Usage Format Source Examples
Samples from Table 4 p. 2784-2785 of Boe and al (1994).
Plates with more than 512 mutants could not be counted with precision, hence the value 512 must be understood as “512 or more”.
1 |
A list of 23 samples of mutants counts, each named "B<index of the sample>".
The i-th sample of the list includes the i-th column of the table.
L. Boe, T. Tolker-Nielsen, K. M. Eegholm, H. Spliid, and A. Vrang: Fluctuation analysis of mutations to nalidixic acid resistance in Escherichia Coli, J. Bacteriol., 176(10):2781-2787 (1994)
1 2 3 4 5 6 7 8 9 10 11 12 | b <- unlist(boeal) # concatenate all samples
ml <- mutestim(b) # maximum likelihood
gf <- mutestim(b,method="GF") # generating function
p0 <- mutestim(b,method="P0") # P0 method
cbind(ml,gf,p0) # compare 3 methods
# test values of mutations and fitness
flan.test(b,alternative=c("greater","less"),mutations0=0.6,fitness0=1)
b1 <- unlist(boeal[1:10]) # first 10 samples
b2 <- unlist(boeal[11:20]) # next 10 samples
flan.test(list(b1,b2)) # test equality
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