Description Slots/List Components Methods Author(s) See Also
A simple list-based class for storing M-values and A-values for a batch of spotted microarrays.
MAList
objects are usually created during normalization by the functions normalizeWithinArrays
or MA.RG
.
MAList
objects can be created by new("MAList",MA)
where MA
is a list.
This class contains no slots (other than .Data
), but objects should contain the following components:
M : | numeric matrix containing the M-values (log-2 expression ratios). Rows correspond to spots and columns to arrays. |
A : | numeric matrix containing the A-values (average log-2 expression values). |
Optional components include:
weights : | numeric matrix of same dimensions as M containing relative spot quality weights. Elements should be non-negative. |
other : | list containing other matrices, all of the same dimensions as M . |
genes : | data.frame containing probe information. Should have one row for each spot. May have any number of columns. |
targets : | data.frame containing information on the target RNA samples. Rows correspond to arrays. May have any number of columns. Usually includes columns Cy3 and Cy5 specifying which RNA was hybridized to each array. |
printer : | list containing information on the process used to print the spots on the arrays. See PrintLayout. |
Valid MAList
objects may contain other optional components, but all probe or array information should be contained in the above components.
This class inherits directly from class list
so any operation appropriate for lists will work on objects of this class.
In addition, MAList
objects can be subsetted and combined.
RGList
objects will return dimensions and hence functions such as dim
, nrow
and ncol
are defined.
MALists
also inherit a show
method from the virtual class LargeDataObject
, which means that RGLists
will print in a compact way.
Other functions in LIMMA which operate on MAList
objects include
normalizeWithinArrays
,
normalizeBetweenArrays
,
normalizeForPrintorder
,
plotMA
and plotPrintTipLoess
.
Gordon Smyth
02.Classes gives an overview of all the classes defined by this package.
marrayNorm
is the corresponding class in the marray package.
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