edger_two_group_de_te: Find differentiated expressed genes in two classes of RNA-seq...

Description Usage Arguments Value

Description

Takes in a vector of control / housekeeping genes to use for expression analysis of a targeted RNA panel. edgeR normalization assumes that most of the genes are not differentially expressed, which might not be true in a targeted panel (https://support.bioconductor.org/p/87121/).

Usage

1
edger_two_group_de_te(genetable, labels, controls, method = "TMMwsp")

Arguments

genetable

a data_frame with columns gene_id and columns corresponding to the numeric value of RNA counts per gene in a sample.

labels

a vector of length ncol(genetable)-1, corresponding to the sample groups

controls

vector of genes that you expect to have consistent expression between groups

method

character, normalization method used by edgeR

Value

data frame with differential p-values for each gene


rmauntz/Larson_cfRNA_DarkChannelBiomarkers documentation built on Jan. 30, 2021, 12:47 a.m.