PAMES | R Documentation |
The PAMES package provides a set of functions to estimate the level of purity or the tumor content of tumor samples.
The basic workflow of PAMES requires to get_AUC
(to evaluate tumor-control methylation differences),
find_informative_sites
(to retrieve sites of interest),
and get_purity
of tumor samples.
When working with methylation data obtained with other technologies (such as Bisulphite Sequencing),
users should must map their set of CpG sites to differentially methylated regions
(such as CpG islands) using data reduce_to_regions
, then
get_AUC
, find_informative_regions
and finally
get_purity
.
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