Description Usage Arguments Value References See Also Examples
This calculates the DVR using the non-invasive reference Logan method for all TACs in a supplied tac file. It uses DVR_ref_Logan.
1 2 | DVR_all_ref_Logan(tac_data, ref, k2prime, t_star, error = 0.1,
method = "trapz", ...)
|
tac_data |
The time-activity curve data from tac_roi() |
ref |
Required – The reference region, e.g. "cerebellum" |
k2prime |
Required – A fixed value for k2' must be specified (e.g. 0.2) |
t_star |
Required – If 0, t* will be calculated using find_t_star() |
error |
For find_t_star() |
method |
Method of integration, "trapz" or "integrate" |
... |
When called from tm_batch, unused parameters may be supplied |
Data frame with calculated DVRs for all ROIs
Logan, J., Fowler, J. S., Volkow, N. D., Wang, G.-J., Ding, Y.-S., & Alexoff, D. L. (1996). Distribution Volume Ratios without Blood Sampling from Graphical Analysis of PET Data. Journal of Cerebral Blood Flow & Metabolism, 16(5), 834-840. https://doi.org/10.1097/00004647-199609000-00008
Other Logan plot functions: DVR_ref_Logan
,
dvr
, plot.ref_Logan
1 2 3 4 5 6 7 8 | f <- system.file("extdata", "AD06.tac", package="tacmagic")
fv <- system.file("extdata", "AD06_TAC.voistat", package="tacmagic")
AD06_tac <- load_tac(f, format="PMOD")
AD06_volume <- load_vol(fv, format="voistat")
AD06 <- tac_roi(tac=AD06_tac, volumes=AD06_volume, ROI_def=roi_ham_pib(),
merge=FALSE, PVC=FALSE)
AD06_DVR <- DVR_all_ref_Logan(AD06, ref="cerebellum", k2prime=0.2, t_star=23)
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