facets2n-package: package documentation
In rptashkin/facets2n: Cellular Faction and Copy Numbers from Tumor Sequencing
facets2n-package R Documentation
package documentation
Description
package documentation
Details
FACETS stands for Fraction and Allelic Copy number Estimation from Tumor/normal Sequencing. It uses high coverage next generation sequencing data (whole exome or targeted) to estimate the total and integer allele specific copy numbers as well as the tumor purity and ploidy. The methodology is described in the reference paper. This package created to test FACETS with both matched and unmatched normal for log ratio normalization.
References
Shen, R and Seshan, VE (2016). FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing.Nucleic Acids Research https://doi.org/10.1093/nar/gkw520
rptashkin/facets2n documentation built on May 11, 2022, 1:34 p.m.
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| facets2n-package | R Documentation |
package documentation
Description
package documentation
Details
FACETS stands for Fraction and Allelic Copy number Estimation from Tumor/normal Sequencing. It uses high coverage next generation sequencing data (whole exome or targeted) to estimate the total and integer allele specific copy numbers as well as the tumor purity and ploidy. The methodology is described in the reference paper. This package created to test FACETS with both matched and unmatched normal for log ratio normalization.
References
Shen, R and Seshan, VE (2016). FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing.Nucleic Acids Research https://doi.org/10.1093/nar/gkw520
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