pbc.long: Mayo Clinic Primary Biliary Cirrhosis Data

In sa4khan/AFTjmr: Recurrent event analysis and joint modeling using accelerated failure time (AFT) models

Description

The data is from the Mayo Clinic trial in primary biliary cirrhosis (PBC) of the liver conducted between 1974 and 1984. A total of 424 PBC patients, referred to Mayo Clinic during that ten-year interval, met eligibility criteria for the randomized placebo controlled trial of the drug D-penicillamine. The first 312 cases in the data set participated in the randomized trial and contain largely complete data. This longitudinal data set contains multiple laboratory results, but only on the first 312 patients.

Usage

data(pbc.long)

Format

A data frame with 1945 rows.

• id: subject identifier

• st: number of years between registration and the earlier of death, transplantion, or study analysis time

• status: 0 = alive, 1 = transplanted, 2 = dead

• status2: 1 = dead, 0 = alive or transplanted

• drug: 1= D-penicillamine, 0=placebo

• age: age in years, at registration

• sex: 0 = male, 1 = female

• futime: number of years between enrollment and this visit date, remaining values on the line of data refer to this visit

• ascites: presence of ascites: 0 = no, 1 = yes

• hepatomegaly: presence of hepatomegaly: 0 = no, 1 = yes

• spiders: presence of spiders: 0 = no, 1 = yes

• edema: presence of edema: 0 = no edema and no diuretic therapy for edema; 0.5 = edema present without diuretics, or edema resolved by diuretics; 1 = edema despite diuretic therapy

• bilirubin: serum bilirubin in mg/dl

• cholesterol: serum cholesterol in mg/dl

• albumin: albumin in gm/dl

• alkaline: alkaline phosphatase in U/liter

• sgot: SGOT in U/ml (serum glutamic-oxaloacetic transaminase, the enzyme name has subsequently changed to "ALT" in the medical literature)

• platelets: platelets per cubic ml/1000

• proTime: prothrombin time in seconds

• histStage: histologic stage of disease

Source

https://www.mayo.edu/research/documents/pbcseqhtml/doc-10027141

References

Therneau T and Grambsch P, Modeling survival data: extending the Cox Model, Springer-Verlag, 2000.

Examples

summary(pbc.long)

sa4khan/AFTjmr documentation built on March 12, 2020, 1:24 a.m.