phonemesPKN: The main PKN used in Phonemes to link deregulated...

phonemesPKNR Documentation

The main PKN used in Phonemes to link deregulated phosphosites to perturbed kinases. It combines kinase-substrate and protein-protein interactions.

Description

The main PKN used in Phonemes to link deregulated phosphosites to perturbed kinases. It combines kinase-substrate and protein-protein interactions.

Format

The full PKN contains 56,738 interactions: 36,915 kinase-substrate interactions (1,688 kinases; 15,385 phosphosites); 19,823 protein-protein interactions

source

upstream protein

interaction

activation/inhibition (1/-1)

target

downstream protein/phosphorylation site

Source

https://github.com/saezlab/PHONEMeS/blob/master/data-raw/phonemesPKN.R

Examples

data("phonemesPKN")

saezlab/PHONEMeS documentation built on May 2, 2024, 11:12 a.m.