methylSig | R Documentation |
MethylSig is a package for testing for differentially methylated cytosines (DMCs) or regions (DMRs) in whole-genome bisulfite sequencing (WGBS) or reduced representation bisulfite sequencing (RRBS) experiments. MethylSig uses a beta binomial model to test for significant differences between groups of samples. Several options exist for either site-specific or sliding window tests, and variance estimation.
filter_loci_by_coverage() filter_loci_by_snps() tile_by_regions() tile_by_windows() filter_loci_by_group_coverage() diff_binomial() diff_methylsig() diff_methylsig_dss() annotate_diff() visualize_diff() region_enrichment_diff()
Maintainer: Raymond G. Cavalcante rcavalca@umich.edu
Authors:
Yongseok Park yongpark@pitt.edu
Useful links:
Report bugs at https://github.com/sartorlab/methylSig/issues
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