methylSig: MethylSig: Differential Methylation Testing for WGBS and RRBS...

methylSigR Documentation

MethylSig: Differential Methylation Testing for WGBS and RRBS Data

Description

MethylSig is a package for testing for differentially methylated cytosines (DMCs) or regions (DMRs) in whole-genome bisulfite sequencing (WGBS) or reduced representation bisulfite sequencing (RRBS) experiments. MethylSig uses a beta binomial model to test for significant differences between groups of samples. Several options exist for either site-specific or sliding window tests, and variance estimation.

methylSig functions

filter_loci_by_coverage() filter_loci_by_snps() tile_by_regions() tile_by_windows() filter_loci_by_group_coverage() diff_binomial() diff_methylsig() diff_methylsig_dss() annotate_diff() visualize_diff() region_enrichment_diff()

Author(s)

Maintainer: Raymond G. Cavalcante rcavalca@umich.edu

Authors:

See Also

Useful links:


sartorlab/methylSig documentation built on March 26, 2023, 10:04 a.m.