sartorlab/methylSig: MethylSig: Differential Methylation Testing for WGBS and RRBS Data

MethylSig is a package for testing for differentially methylated cytosines (DMCs) or regions (DMRs) in whole-genome bisulfite sequencing (WGBS) or reduced representation bisulfite sequencing (RRBS) experiments. MethylSig uses a beta binomial model to test for significant differences between groups of samples. Several options exist for either site-specific or sliding window tests, and variance estimation.

Getting started

Package details

Bioconductor views DNAMethylation DifferentialMethylation Epigenetics MethylSeq Regression
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
sartorlab/methylSig documentation built on May 27, 2021, 10:03 a.m.