HUMAN_Background_signaling_interactome: Intracellular signaling interactions of human genes

HUMAN_Background_signaling_interactomeR Documentation

Intracellular signaling interactions of human genes

Description

Intracellular signaling interactions of human genes

Usage

HUMAN_Background_signaling_interactome

Format

A data frame with 128093 rows and 3 variables:

Source

character Gene symbol of the regulating gene

Target

character Gene symbol of the regulated gene

Effect

integer Whether the effect is activating - denoted as '1' - or inhibiting - denoted as '-1'

Details

This dataset is used for creating a Markov Chain model of intracellular signaling to identify significantly active paths from receptors to downstream TFs.

Author(s)

Sascha Jung sjung@cicbiogune.es


saschajung/Intercom documentation built on May 27, 2023, 5:11 p.m.