HUMAN_Background_signaling_interactome | R Documentation |
Intracellular signaling interactions of human genes
HUMAN_Background_signaling_interactome
A data frame with 128093 rows and 3 variables:
Source
character Gene symbol of the regulating gene
Target
character Gene symbol of the regulated gene
Effect
integer Whether the effect is activating - denoted as '1' - or inhibiting - denoted as '-1'
This dataset is used for creating a Markov Chain model of intracellular signaling to identify significantly active paths from receptors to downstream TFs.
Sascha Jung sjung@cicbiogune.es
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