Description Usage Arguments Details Value Author(s) See Also
ode.model
is the system evaluation function called when an $ODE block
is detected in the model file, indicating that the model is defined by
ordinary differential equations. ode.model
is typically not called
directly by users
1 2 3 4 5 6 7 8 9 10 |
parms |
A vector of primary parameters. |
derparms |
A list of derived parameters, specified in the $DERIVED block of code. |
code |
A list of R code extracted from the model file. Depending on content of the model file, the levels of this list could be: template, derived, lags, ode, dde, output, variance, and/or secondary. |
bolus |
A data.frame providing the instantaneous inputs entering the system of delay differential equations for the treatment and individual being evaluated. |
infusion |
A data.frame providing the zero-order inputs entering the system of delay differential equations for the treatment and individual being evaluated. |
xdata |
A vector of times at which the system is being evaluated. |
covdata |
A data.frame of covariate data for the treatment and individual being evaluated. |
issim |
An indicator for simulation or estimation runs. |
check |
An indicator whether checks should be performed to validate function inputs. |
options |
A list of differential equation solver options. Currently not modifiable by users. |
ode.model
evaluates the model for each treatment of each individual
contained in the dataset using several utility functions: derived.parms
,
init.cond
, input.scaling
, make.dosing
, init.update
,
and de.output
.
The actual evaluation of the system is performed by ode
from the
deSolve package.
Returns a matrix of system predictions.
Sebastien Bihorel (sb.pmlab@gmail.com)
ode
,
init.cond
, input.scaling
,
make.dosing
, init.update
,
de.output
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