Description Usage Arguments Value
Create a Study
object for a CRGI type single arm study
1 2 | SingleArmCRGIStudy(N, study.duration, ctrl.time, ctrl.proportion, k, acc.period,
shape = 1, followup, dropout = NULL, lag.settings = NullLag())
|
N |
Number of subjects to be recruit (integer) |
study.duration |
Number of months the study will be going. |
ctrl.time |
The time at which |
ctrl.proportion |
The proportion of subjects who have had an event by time |
k |
non-uniformity of accrual (integer, 1=uniform). Non-uniform accrual is allowed for using the following distribution for the probability of a patient entering the trial at time b within the accrual period [0,B]: F(b)=b_k/B_k; f(b)=k b_{k-1}/B_k where k is the measure of non-uniformity (k>0). k=1 indicates uniform accrual. This implies that during the first half of the accrual period, 1/2^k of the patients will be recruited. Half of the patients will be recruited by time B/2^{1/k}. |
acc.period |
Accrual time. |
shape |
The Weibull shape parameter |
followup |
The follow up time for each subject |
dropout |
if subjects drop out in study (due to competing risks not as there is a finite follow up time)
then this argument should contain a list with proportion and time and optionally shape i.e.
|
lag.settings |
The |
A Study
object
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