shazanfar/scHOT: single-cell higher order testing

Single cell Higher Order Testing (scHOT) is an R package that facilitates testing changes in higher order structure of gene expression along either a developmental trajectory or across space. scHOT is general and modular in nature, can be run in multiple data contexts such as along a continuous trajectory, between discrete groups, and over spatial orientations; as well as accommodate any higher order measurement such as variability or correlation. scHOT meaningfully adds to first order effect testing, such as differential expression, and provides a framework for interrogating higher order interactions from single cell data.

Getting started

Package details

Bioconductor views GeneExpression RNASeq Sequencing SingleCell Software Transcriptomics
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
shazanfar/scHOT documentation built on June 29, 2023, 5:29 p.m.