calcKi: Calculate the Ki of an inhibitor with the Cheng-Prusoff...
In shirewoman2/Consultancy: Standardized tools for using R within the Simcyp Consultancy Team
calcKi R Documentation
Calculate the Ki of an inhibitor with the Cheng-Prusoff equation
Description
calcKi uses IC50, substrate concentration, and Km to calculate a Ki
value for an inhibitor
Usage
calcKi(IC50, S, Km = NA)
Arguments
IC50
The IC50 value for the inhibitor (uM)
S
The concentration of the substrate used (uM)
Km
The Michaelis constant for the affinity between the substrate and
the enzyme (uM)
Value
Returns the inhibitory constant Ki (uM) (numeric)
Examples
calcKi(20, 5, 5)
# 10
shirewoman2/Consultancy documentation built on Feb. 18, 2025, 10 p.m.
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| calcKi | R Documentation |
Calculate the Ki of an inhibitor with the Cheng-Prusoff equation
Description
calcKi uses IC50, substrate concentration, and Km to calculate a Ki
value for an inhibitor
Usage
calcKi(IC50, S, Km = NA)
Arguments
IC50 |
The IC50 value for the inhibitor (uM) |
S |
The concentration of the substrate used (uM) |
Km |
The Michaelis constant for the affinity between the substrate and the enzyme (uM) |
Value
Returns the inhibitory constant Ki (uM) (numeric)
Examples
calcKi(20, 5, 5)
# 10
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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