Bayesian Negative Binomial regression for differential expression analysis of sequencing count data with confounding factors
1 2 | NBregDE2(counts, X, cond, idx.cond, Burnin = 1000L, Collections = 1000L,
PGTruncation = 60L, randtry = 2017)
|
counts |
a matrix of counts, rows are corresponding to genes and columns are corresponding to samples. |
X |
design matrix |
cond |
the index of covariate corresponding to the main treatment |
idx.cond |
a vector of covariate indices that the effect of their combination on gene expression is under study |
Burnin |
Number of burn-in iterations in MCMC |
Collections |
Number of collected posterior samples after burn-in |
PGTruncation |
the truncation level used for genrating random numbers from Polya-Gamma distribution |
randtry |
to be used for set.seed() |
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