choose_proband: Choose a proband from the disease-affected relatives in a...

Description Usage Arguments Value

View source: R/RVPedSim_Functions.R

Description

Choose a proband from the disease-affected relatives in a pedigree

Usage

1
choose_proband(ped_file, num_affected, ascertain_span, first_diagnosis)

Arguments

ped_file

Pedigree simulated by sim_ped.

num_affected

Numeric vector. The minimum number of disease-affected relatives required for ascertainment.

ascertain_span

Numeric vector of length 2. The year span of the ascertainment period. This period represents the range of years during which the proband developed disease and the family would have been ascertained for multiple affected relatives.

first_diagnosis

Numeric. The first year that reliable diagnoses can be obtained regarding disease-affection status. By default, first_diagnosis = NULL so that all diagnoses are considered reliable. See details.

Value

Pedigree with proband selected.


simrvprojects/SimRVPedigree documentation built on Nov. 5, 2019, 8:55 a.m.