Description Usage Arguments Value
View source: R/PedSim_Functions.R
Determine founder genotype at the disease locus and determime their relative-risk of disease
1 | sim_founderRVstatus(GRR, carrier_prob, RVfounder)
|
GRR |
Numeric. The genetic relative-risk of disease, i.e. the relative-risk of disease for individuals who carry at least one copy of the causal variant. Note: When simulating diseases with multiple subtypes |
carrier_prob |
Numeric. The carrier probability for all causal variants with relative-risk of disease |
RVfounder |
Logical. Indicates if all pedigrees segregate the rare, causal variant. By default, |
intro_RV |
Logical. If |
A list containing: 1. the founder's genotype at the disease locus, their relative-risk of disease, and an updated value for intro_RV.
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