aerpt.summary: Create summary of AEs for Alliance DSMB reports

In sjacobson94/clinicaltrials: A Collection of Functions for use in CCS

Description

This function is design to replicate aerpt_alliance_macro.sas AE summary output for Alliance DSMB reports.

Usage

aerpt.summary(
  cytox,
  id,
  grade.cutoff = 1,
  rel.cutoff = 0,
  rel.include = 1,
  byvar = "arm",
  arm.include = 1,
  arm.labels = NULL,
  toxvar = "toxicity",
  relvar = "rel_smed",
  gradevar = "grade",
  bodysysvar = "bodysys"
)

Arguments

cytox	The toxicity dataset containing multiple observations per patient with one observation per AE > grade 0
id	The patient ID variable used in the dataset
grade.cutoff	Grade cutoff for minimum AE grade. Inclusive
rel.cutoff	Attribution cutoff for minimum AE attribution. Inclusive
rel.include	Value of 0 or 1. If 0, "Regardless of Attribution" printed in header. If 1, "At least possibly related" printed in header
byvar	Variable used to separate summary by arm. If not present, "All Patients" printed for arm. Set to NULL if calculations are desired for all patients together.
arm.include	Include "Arm" in table (1) or not (0). Default is 1.
arm.labels	Option to include additional Arm labels in the table header. Add as vector of characters.
toxvar	Variable containing numeric toxicity codes.
relvar	Variable containing numeric relation values 1-5.
gradevar	Grade variable, numeric.
bodysysvar	Body system variable, character.

Value

This function creates a summary of the AE events for the Alliance DSMB report

Author(s)

Sawyer Jacobson

Adam Pettinger

Examples

#With data loaded for A041501

crtlibn(d = 'A041501')

all.summary <- aerpt.summary(cytox, id="dcntr_id", byvar="arm", 
grade.cutoff = 3, rel.cutoff = 0, rel.include = 0)
all.summary$table

sjacobson94/clinicaltrials documentation built on Oct. 27, 2020, 6:43 p.m.