SurvIC: Create a survival object for interval censoring and possibly...

In socale/frailtypack: Shared, Joint (Generalized) Frailty Models; Surrogate Endpoints

Description

This is a function used in case of interval-censoring as a response variable in a model formula only for Cox proportional hazard or shared frailty model. Sometimes, an unobserved event might occur in a time interval [L,U]. RecurrentAG argument gets invalid with the use of SurvIC. Note that this function used a Kronecker product which can suffer from computation issue when the number of subjects in each cluster is high. Time dependent variables are not allowed.

Usage

SurvIC(t0, lower, upper, event)

Arguments

t0	Truncation time for left truncated data only. To be ignored otherwise.
lower	Starting time of the interval for interval-censored data. Time of right-censoring instead.
upper	Ending time of the interval for interval-censored data. For right-censored data, lower and upper time must be equal (for numerical reason).
event	Status indicator 0=right-censored, 1=interval-censored

Details

Typical usages are SurvIC(lower,upper,event) or SurvIC(t0,lower,upper,event)

Examples

## Not run: 

data(bcos)
bcos$event <- ifelse(bcos$left!=bcos$right,1,0)

###---  Cox proportional hazard model with interval censoring ---###

cox.ic <- frailtyPenal(SurvIC(left,right,event)~treatment,
data=bcos,n.knots=8,kappa=10000)

###---  Shared model with interval censoring ---###

bcos$group <- c(rep(1:20,4),1:14)

sha.ic <- frailtyPenal(SurvIC(left,right,event)~cluster(group)+
treatment,data=bcos,n.knots=8,kappa=10000)


## End(Not run)

socale/frailtypack documentation built on June 15, 2021, 3:37 a.m.